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The p53 Arg72Pro and Ins16bp polymorphisms and their haplotypes are not associated with breast cancer risk in BRCA-mutation negative familial cases

✍ Scribed by Giovanna De Vecchi; Paolo Verderio; Sara Pizzamiglio; Siranoush Manoukian; Loris Bernard; Valeria Pensotti; Sara Volorio; Fernando Ravagnani; Paolo Radice; Paolo Peterlongo


Book ID
113524500
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
85 KB
Volume
32
Category
Article
ISSN
0361-090X

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## Communicated by Dvorah Abeliovich Germline mutations in the BRCA1 and BRCA2 genes confer a high lifetime risk of developing breast and other cancers; however, remarkable differences exist regarding disease manifestation in mutation carriers. It has been suggested that other genetic and/or enviro