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The TP53 Arg72Pro and MDM2 309G>T polymorphisms are not associated with breast cancer risk in BRCA1 and BRCA2 mutation carriers

✍ Scribed by Sinilnikova, O M; Antoniou, A C; Simard, J; Healey, S; Léoné, M; Sinnett, D; Spurdle, A B; Beesley, J; Chen, X; Greene, M H


Book ID
110000156
Publisher
Nature Publishing Group
Year
2009
Tongue
English
Weight
115 KB
Volume
101
Category
Article
ISSN
0007-0920

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## Communicated by Dvorah Abeliovich Germline mutations in the BRCA1 and BRCA2 genes confer a high lifetime risk of developing breast and other cancers; however, remarkable differences exist regarding disease manifestation in mutation carriers. It has been suggested that other genetic and/or enviro