Breast cancer risk in BRCA1 and BRCA2 mu
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David J. Hughes; Sophie M. Ginolhac; Isabelle Coupier; Laure Barjhoux; ValΓ©rie G
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Article
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2005
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John Wiley and Sons
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French
β 89 KB
π 1 views
## Abstract Marked variation in phenotypic expression among __BRCA1__ and __BRCA2__ mutation carriers may be partly explained by modifier genes that influence mutation penetrance. Variation in CAG/CAA repeat lengths coding for stretches of glutamines in the Cβterminus of the AIB1 protein (amplified