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Application of BRCA1 and BRCA2 mutation carrier prediction models in breast and/or ovarian cancer families of French Canadian descent

✍ Scribed by KK Oros; P Ghadirian; CM Maugard; C Perret; Y Paredes; A-M Mes-Masson; WD Foulkes; D Provencher; PN Tonin

Book ID
118701146
Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
220 KB
Volume
70
Category
Article
ISSN
0009-9163

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πŸ“œ SIMILAR VOLUMES

Significant proportion of breast and/or
Significant proportion of breast and/or ovarian cancer families of French Canadian descent harbor 1 of 5 BRCA1 and BRCA2 mutations
✍ Kathleen K. Oros; Parviz Ghadirian; Celia M.T Greenwood; Chantal Perret; Zhen Sh πŸ“‚ Article πŸ“… 2004 πŸ› John Wiley and Sons 🌐 French βš– 193 KB πŸ‘ 1 views

## Abstract In 1998, we reported that a significant proportion of breast and/or ovarian cancer families of French Canadian descent harbor specific germline mutations in __BRCA1__ or __BRCA2__ attributed to common founders. Here we report the frequency of previously described mutations (__n__ = 7) a

Germline mutations of BRCA1 and BRCA2 in
Germline mutations of BRCA1 and BRCA2 in Korean breast and/or ovarian cancer families
✍ Hio Chung Kang; Il-Jin Kim; Jae-Hyun Park; Hyuk-Jun Kwon; Yong-Jin Won; Seung Ch πŸ“‚ Article πŸ“… 2002 πŸ› John Wiley and Sons 🌐 English βš– 140 KB πŸ‘ 2 views

Germline mutations in the BRCA1 and BRCA2 genes are responsible for the predisposition and development of familial breast and/or ovarian cancer. Most mutations of BRCA1 and BRCA2 associated with breast and/or ovarian cancer result in truncated proteins. To investigate the presence of BRCA1 and BRCA2