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Models for predicting BRCA1 and BRCA2 mutations in Han Chinese familial breast and/or ovarian cancer patients

✍ Scribed by Nan-Yan Rao; Zhen Hu; Wen-Feng Li; Juan Huang; Zhong-Liang Ma; Bin Zhang; Feng-Xi Su; Jie Zhou; Gen-Hong Di; Kun-Wei Shen; Jiong Wu; Jin-Song Lu; Jian-Min Luo; Wen-Tao Yuan; Zhen-Zhou Shen; Wei Huang; Zhi-Ming Shao

Publisher: Springer US
Year: 2008
Tongue: English
Weight: 337 KB
Volume: 113
Category: Article
ISSN: 0167-6806
DOI: 10.1007/s10549-008-9965-9

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## Abstract Among Asian countries, Pakistan has the highest rates of breast and ovarian cancer. To assess the contribution of the __BRCA1__ and __BRCA2__ germ line mutations to these high rates, we conducted the first study of 176 Pakistani breast and ovarian cancer patients, selected on family his