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Founder BRCA1 and BRCA2 Mutations in French Canadian Breast and Ovarian Cancer Families

✍ Scribed by Patricia N. Tonin; Anne-Marie Mes-Masson; P. Andrew Futreal; Kenneth Morgan; Michelle Mahon; William D. Foulkes; David E.C. Cole; Diane Provencher; Parviz Ghadirian; Steven A. Narod


Book ID
117852601
Publisher
American Society of Human Genetics
Year
1998
Tongue
English
Weight
439 KB
Volume
63
Category
Article
ISSN
0002-9297

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Germline mutations in the BRCA1 and BRCA2 genes account for the majority of high-risk breast/ovarian cancer families, depending on the population studied. Previously, BRCA1 mutations were described in women from Western Poland. To further characterize the spectrum of BRCA1 mutations and the impact o