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Hamster Liver Cytochrome P450 (CYP2A8) as a 4-Hydroxylase for 2,5,2′,5′-Tetrachlorobiphenyl

✍ Scribed by Nobuyuki Koga; Naoko Kikuichi; Tomoyo Kanamaru; Noritaka Ariyoshi; Kazuta Oguri; Hidetoshi Yoshimura


Book ID
115578900
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
61 KB
Volume
225
Category
Article
ISSN
0006-291X

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## Abstract The effects of a single injection (40 mg/kg) of 4′‐trifluoromethyl‐2,3,4,5‐tetrachlorobiphenyl (CF3) on hepatic cytochrome P‐450 monooxygenases were assessed in rat and syrian hamster. The CF3 treatment significantly increased the total amount of cytochrome P‐450 in both species. In rat