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Purification and Characterization of a Newly Identified Isoform of Cytochrome-P450 Responsible for 3-Hydroxylation of 2,5,2′,5′-Tetrachlorobiphenyl in Hamster Liver

✍ Scribed by N. Koga; N. Kikuichinishimura; T. Hara; N. Harada; Y. Ishii; H. Yamada; K. Oguri; H. Yoshimura


Book ID
115565524
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
627 KB
Volume
317
Category
Article
ISSN
0003-9861

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## Abstract The effects of a single injection (40 mg/kg) of 4′‐trifluoromethyl‐2,3,4,5‐tetrachlorobiphenyl (CF3) on hepatic cytochrome P‐450 monooxygenases were assessed in rat and syrian hamster. The CF3 treatment significantly increased the total amount of cytochrome P‐450 in both species. In rat