Improved Photocontrol of α-Chymotrypsin
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David Pearson; Nathan Alexander; Andrew D. Abell
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Article
📅
2008
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John Wiley and Sons
🌐
English
⚖ 310 KB
## Abstract A series of peptidomimetic trifluoromethylketones containing the photoisomerisable azobenzene group have been synthesised, photoisomerised and assayed against the serine protease α‐chymotrypsin. All are inhibitors of the enzyme and exhibit up to a fivefold increase in activity on UV irr