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Electrospray ionization mass spectrometric analysis for interaction of α-chymotrypsin with bebame, an active-site directed enzyme inhibitor

✍ Scribed by Yeoun Jin Kim; Zhi-Hong Li; Dong H. Kim; Jong Hoon Hahn


Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
215 KB
Volume
6
Category
Article
ISSN
0960-894X

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✦ Synopsis


Using the electrospray ionization mass spectrometric method, we have shown that (2S,3R)-2benzyl-3,4-epoxybutanoic acid methyl ester (BEBAME) inactivates cc-chymotrypsin most probably by modifying eovalently the hydroxyl of