𝔖 Bobbio Scriptorium
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Grapefruit juice reduces bioavailability of oral etoposide


Book ID
120861881
Publisher
Adis International Limited (now part of Wolters Kluwer Health)
Year
2002
Weight
133 KB
Volume
&NA;
Category
Article
ISSN
1173-8324

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Previous studies with rats indicate that nifedipine undergoes both hepatic and extrahepatic presystemic metabolism after peroral (po) administration, and that its bioavailability is increased and absorption delayed by concomitant administration of grapefruit juice concentrate (GJC). Hence, the effec