Previous studies with rats indicate that nifedipine undergoes both hepatic and extrahepatic presystemic metabolism after peroral (po) administration, and that its bioavailability is increased and absorption delayed by concomitant administration of grapefruit juice concentrate (GJC). Hence, the effec
✦ LIBER ✦
Grapefruit juice increases the bioavailability of artemether
✍ Scribed by M. A. van Agtmael; V. Gupta; T. H. van der Wösten; J.-P. B. Rutten; C. J. van Boxtel
- Publisher
- Springer
- Year
- 1999
- Tongue
- English
- Weight
- 125 KB
- Volume
- 55
- Category
- Article
- ISSN
- 0031-6970
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