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Glucocorticoid repression of pro-opiomelanocortin gene transcription

โœ Scribed by Jacques Drouin; Sun Yu Lin; Mona Nemer


Book ID
116007388
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
816 KB
Volume
34
Category
Article
ISSN
0022-4731

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Pro-opiomelanocortin gene: A model for n
โœ Jacques Drouin; Jean Charron; Jean-Pierre Gagner; Lucie Jeannotte; Mona Nemer; R ๐Ÿ“‚ Article ๐Ÿ“… 1987 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 858 KB

The gene encoding pro-opiomelanocortin (POMC) offers an interesting model system to study negative control of transcription in eucaryotes. Indeed, glucocorticoid hormones specifically inhibit transcription of the POMC gene in the anterior pituitary. The POMC gene is predominantly expressed in the an