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Tissue-specific activity of the pro-opiomelanocortin (POMC) gene and repression by glucocorticoids

โœ Scribed by Drouin, Jacques; Nemer, Mona; Charron, Jean; Gagner, Jean-Pierre; Jeannotte, Lucie; Sun, Yu Lin; Therrien, Marc; Tremblay, Yves


Book ID
118736815
Publisher
NRC Research Press
Year
1989
Tongue
English
Weight
894 KB
Volume
31
Category
Article
ISSN
0831-2796

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Pro-opiomelanocortin gene: A model for n
โœ Jacques Drouin; Jean Charron; Jean-Pierre Gagner; Lucie Jeannotte; Mona Nemer; R ๐Ÿ“‚ Article ๐Ÿ“… 1987 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 858 KB

The gene encoding pro-opiomelanocortin (POMC) offers an interesting model system to study negative control of transcription in eucaryotes. Indeed, glucocorticoid hormones specifically inhibit transcription of the POMC gene in the anterior pituitary. The POMC gene is predominantly expressed in the an