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DNA sequence element responsible for inhibition of pro-opiomelanocortin gene transcription by glucocorticoids

✍ Scribed by J. Drouin; J.P. Gagner; L. Jeannotte; R.K. Plante; O. Wrange


Book ID
116005950
Publisher
Elsevier Science
Year
1986
Tongue
English
Weight
120 KB
Volume
25
Category
Article
ISSN
0022-4731

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Pro-opiomelanocortin gene: A model for n
✍ Jacques Drouin; Jean Charron; Jean-Pierre Gagner; Lucie Jeannotte; Mona Nemer; R πŸ“‚ Article πŸ“… 1987 πŸ› John Wiley and Sons 🌐 English βš– 858 KB

The gene encoding pro-opiomelanocortin (POMC) offers an interesting model system to study negative control of transcription in eucaryotes. Indeed, glucocorticoid hormones specifically inhibit transcription of the POMC gene in the anterior pituitary. The POMC gene is predominantly expressed in the an