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Germline RAD51C mutations in ovarian cancer susceptibility

✍ Scribed by F Coulet; A Fajac; C Colas; M Eyries; A Dion-Minière; R Rouzier; S Uzan; J-P Lefranc; M Carbonnel; F Cornelis; A Cortez; F Soubrier


Book ID
119839664
Publisher
John Wiley and Sons
Year
2013
Tongue
English
Weight
624 KB
Volume
83
Category
Article
ISSN
0009-9163

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Analysis of RAD51C germline mutations in
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There is strong evidence that overtly inactivating mutations in RAD51C predispose to hereditary breast and ovarian cancer but the prevalence of such mutations, and whether they are associated with a particular clinical phenotype, remains unclear. Resolving these questions has important implications