𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Genotypic analysis of tumor suppressor genes PTEN/MMAC1 and p53 in head and neck squamous cell carcinomas

✍ Scribed by Ying C. Henderson; Eric Wang; Gary L. Clayman

Book ID
110079818
Publisher
John Wiley and Sons
Year
1998
Tongue
English
Weight
381 KB
Volume
108
Category
Article
ISSN
0023-852X

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Mutational analysis of the PTEN gene in
Mutational analysis of the PTEN gene in head and neck squamous cell carcinoma
✍ Xiyun Shao; Raj Tandon; Ghassan Samara; Hiroaki Kanki; Hiroko Yano; Lanny G. Clo πŸ“‚ Article πŸ“… 1998 πŸ› John Wiley and Sons 🌐 French βš– 121 KB πŸ‘ 2 views

## Loss of heterozygosity (LOH ) at chromosome band 10q23 occurs frequently in a wide variety of human tumors. A recently identified candidate tumor suppressor gene, PTEN located on 10q23, is mutated in multiple advanced cancers. To explore whether PTEN is associated with human squamous cell carci

Expression and prognostic role of tumor
Expression and prognostic role of tumor suppressor gene PTEN/MMAC1/TEP1 in hepatocellular carcinoma
✍ Tsung-Hui Hu; Chao-Cheng Huang; Pey-Ru Lin; Hsueh-Wen Chang; Luo-Ping Ger; Yu-We πŸ“‚ Article πŸ“… 2003 πŸ› John Wiley and Sons 🌐 English βš– 978 KB

## Abstract ## BACKGROUND Inactivation of the tumor suppressor gene __PTEN__/__MMAC1__/__TEP1__, located on chromosome 10q23, is a common event in advanced stages of diverse human malignancies. However, the prognostic role of __PTEN__ expression in patients with hepatocellular carcinoma (HCC) has

Analysis of gene amplification in head-a
Analysis of gene amplification in head-and-neck squamous-cell carcinomas
✍ J. Helen Leonard; John H. Kearsley; Georgia Chenevix-Trench; Nicholas K. Hayward πŸ“‚ Article πŸ“… 1991 πŸ› John Wiley and Sons 🌐 French βš– 656 KB

The presence of gene amplification was determined in 66 fresh head-and-neck SCC specimens using a battery of 9 different probes. Amplification of at least one gene was found in I 2 samples (18%), of which 7 were amplified at multiple loci (58%). We observed amplifications for EGFR (10% of samples) a

Abnormalities in the p53 gene in tumors
Abnormalities in the p53 gene in tumors and cell lines of human squamous-cell carcinomas of the head and neck
✍ Xiao-Ying Yin; Martin L. Smith; Theresa L. Whiteside; Joseph Locker; Jonas T. Jo πŸ“‚ Article πŸ“… 1993 πŸ› John Wiley and Sons 🌐 French βš– 943 KB

Abnormalities in the p53 gene were studied in a series of cell lines of human squamous-cell carcinoma of the head and neck (SCCHN) and in tumor tissues. Restriction-fragment-length polymorphism (RFLP), quantitative hybridization and immunochemical analysis of mutant p53 proteins were combined to det