## Abstract Structural information about the products formed when 7,12‐dimethylbenz(__a__)anthracene (DMBA) is bound to DNA in mammalian cell cultures has been sought through studies of the photosensitivities of these products and of various model compounds. Under conditions of light exposure in wh
[G-3H]-7,12-dimethylbenz[A]anthracene 5,6-oxide
✍ Scribed by Peter P. Fu; Ronald G. Harvey
- Publisher
- John Wiley and Sons
- Year
- 1977
- Tongue
- French
- Weight
- 133 KB
- Volume
- 13
- Category
- Article
- ISSN
- 0022-2135
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## Abstract One of the most potent carcinogens is 7,12‐dimethylbenz(a)anthracene (7,12‐DMBA), which is used routinely to conduct studies to evaluate carcinogen inhibitors. Its pharmacokinetics have not been reported in the literature. In view of its significant effects on drug metabolizing enzymes
## Abstract The 2 + 4 cycloaddition reaction of 1,4‐naphthoquinone and substituted styrenes was used to prepare 1‐, 2‐, 3‐, and 4‐bromobenz[a]anthracene‐7,12‐diones (BADs). The corresponding bromobenz[a]anthracenes (BAs) were prepared by aluminum tricyclohexoxide reduction of the diones. Lithiation
## Abstract Syntheses of (8α,9α,10α,11β)‐__trans__‐1,2,3,4,8,9,10,11‐octahydro‐7,12‐dimethyl‐8,9‐epoxybenz[a]anthracene‐10,11‐diol (3) and (8α,9α,10β,11α)‐__trans__‐1,2,3,4,8,9,10,11‐octahydro‐7,12‐dimethyl‐8,9‐epoxybenz[a]anthracene‐10,11‐diol (4), the putative D‐ring metabolites of 1,2,3,4‐tetrah
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