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Frequency of the apolipoprotein E ε2 allele is diminished in sporadic Alzheimer disease

✍ Scribed by West, Howard L.; William Rebeck, G.; Hyman, Bradley T.


Book ID
122873787
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
308 KB
Volume
175
Category
Article
ISSN
0304-3940

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Gene dose of the ε4 allele of apolipopro
✍ Dr Giovanni B. Frisoni; Stefano Govoni; Cristina Geroldi; Angelo Bianchetti; Lau 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 English ⚖ 974 KB

A strong association has been described in cross-sectional studies between the ~4 allele of the apolipoprotein E and late-onset Alzheimer's disease (LOAD). This study addresses the relationship between disease progression and the ~4 allele in 6 2 sporadic LOAD (onset at age 70 and over) patients. Di