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Allele doses of apolipoprotein E type ε4 in sporadic late-onset Alzheimer's disease

✍ Scribed by Lucotte, Gérard ;Aouizérate, Annie ;Gérard, Nathalie ;Turpin, J. C. ;Landais, P.


Publisher
John Wiley and Sons
Year
1995
Tongue
English
Weight
338 KB
Volume
60
Category
Article
ISSN
0148-7299

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We examined the association of apolipoprotein E (ApoE) genotype and the risk of early-onset Alzheimer's disease (AD) in 209 white early-onset sporadic cases (43% male) and 303 white controls (48% male) of similar age distribution. The risk of AD was significantly increased, relative to the 313 genot