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Dose-dependent association of apolipoprotein e allele ε4 with late-onset, sporadic Alzheimer's disease

✍ Scribed by Dr. Toshihiro Yoshizawa; Kimiko Yamakawa-Kobayashi; Yasuko Komatsuzaki; Tadao Arinami; Ei'ichi Oguni; Hidehiro Mizusawa; Shin'ichi Shoji; Hideo Hamaguchi


Publisher
John Wiley and Sons
Year
1994
Tongue
English
Weight
457 KB
Volume
36
Category
Article
ISSN
0364-5134

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Evidence for apolipoprotein E ε4 associa
✍ Pérez-Tur, Jordi ;Campion, Dominique ;Martinez, Maria ;Brice, Alexis ;Tardieu, S 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 English ⚖ 447 KB

Recently several reports have extended the apolipoprotein E (AF'OE) €4 association found in late-onset Alzheimer's disease (LOAD) patients to early-onset (EO) AD patients. We have studied this question in a large population of 119 EOAD patients (onset 560 years) in which family history was carefully