𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Fmoc Solid-Phase Synthesis of Peptide Thioesters Using an Intramolecular N , S -Acyl Shift

✍ Scribed by Ollivier, Nathalie; Behr, Jean-Bernard; El-Mahdi, Ouafâa; Blanpain, Annick; Melnyk, Oleg

Book ID
118066013
Publisher
American Chemical Society
Year
2005
Tongue
English
Weight
50 KB
Volume
7
Category
Article
ISSN
1523-7060

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Direct preparation of peptide thioesters
Direct preparation of peptide thioesters using an Fmoc solid-phase method
✍ Xiangqun Li; Toru Kawakami; Saburo Aimoto 📂 Article 📅 1998 🏛 Elsevier Science 🌐 French ⚖ 266 KB

Aiming at the direct preparation of peptide thioesters by an Fmoc solid-phase method, we searched a new deblocking reagent, which efficiently removed Fmoc groups while keeping the thioester intact. The deblocking reagent, which contains 1-methylpyrrolidine, hexamethyleneimine and HOBt in a one to on

An improved deblocking agent for direct
An improved deblocking agent for direct Fmoc solid-phase synthesis of peptide thioesters
✍ Xianzhang Bu; Guiyang Xie; Chi Wang Law; Zhihong Guo 📂 Article 📅 2002 🏛 Elsevier Science 🌐 French ⚖ 133 KB

To synthesize peptide thioesters directly on a solid support for use as substrate analogues for thioesterases in non-ribosomal peptide synthases, we modified a reagent compatible with Fmoc solid-phase peptide synthesis that efficiently removes the protecting group while keeping the thioester intact.