𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Preparation of Peptide Thioesters through Fmoc-Based Solid-Phase Peptide Synthesis by Using Amino Thioesters

✍ Scribed by Stuhr-Hansen, Nicolai; Wilbek, Theis S.; Strømgaard, Kristian

Book ID
120580755
Publisher
John Wiley and Sons
Year
2013
Tongue
English
Weight
495 KB
Volume
2013
Category
Article
ISSN
1434-193X

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Direct preparation of peptide thioesters
Direct preparation of peptide thioesters using an Fmoc solid-phase method
✍ Xiangqun Li; Toru Kawakami; Saburo Aimoto 📂 Article 📅 1998 🏛 Elsevier Science 🌐 French ⚖ 266 KB

Aiming at the direct preparation of peptide thioesters by an Fmoc solid-phase method, we searched a new deblocking reagent, which efficiently removed Fmoc groups while keeping the thioester intact. The deblocking reagent, which contains 1-methylpyrrolidine, hexamethyleneimine and HOBt in a one to on

Peptide thioester preparation by Fmoc so
Peptide thioester preparation by Fmoc solid phase peptide synthesis for use in native chemical ligation
✍ Andrew B. Clippingdale; Colin J. Barrow; John D. Wade 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 135 KB 👁 2 views

Established methodology for the preparation of peptide thioesters requires the use of t-butoxycarbonyl chemistry owing to the lability of thioester linkers to the nucleophilic reagents used in Fmoc solid phase peptide synthesis. Both the greater ease of use and the broad applicability of the method