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fldA is an essential gene required in the 2-C-methyl-D-erythritol 4-phosphate pathway for isoprenoid biosynthesis

✍ Scribed by Kia-Joo Puan; Hong Wang; Tohru Dairi; Tomohisa Kuzuyama; Craig T. Morita


Book ID
116465690
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
190 KB
Volume
579
Category
Article
ISSN
0014-5793

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Chemical Synthesis of Enantiopure 2-C-Me
✍ Jean-FranΓ§ois Hoeffler; C Pale-Grosdemange; Michel Rohmer πŸ“‚ Article πŸ“… 2000 πŸ› Elsevier Science 🌐 French βš– 117 KB

Optically pure 2-C-methyl-d-erythritol 4-phosphate, a key intermediate in the mevalonate-independent route for isoprenoid biosynthesis, is conveniently synthesized from 1,2-O-isopropylidene-a-d-xylofuranose, including the possibility of radiolabeling of this substrate.