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Cloning and characterization of 2-C-methyl-d-erythritol-4-phosphate pathway genes for isoprenoid biosynthesis from Indian ginseng,Withania somnifera

✍ Scribed by Parul Gupta, Aditya Vikram Agarwal, Nehal Akhtar, Rajender Singh Sangwan, Surya Pratap Singh, Prabodh Kumar Trivedi

Book ID
111652530
Publisher
Springer Vienna
Year
2012
Tongue
English
Weight
837 KB
Volume
250
Category
Article
ISSN
0033-183X

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πŸ“œ SIMILAR VOLUMES

Elucidation of the 2-C-methyl-d-erythrit
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Optically pure 1-deoxy-D-xylulose, a key metabolite for feeding experiments in the methylerythritol phosphate pathway for isoprenoid biosynthesis, is conveniently synthesised from 1,2-O-isopropylidene-a-D-xylofuranose or from D-arabinose. This renders labelling with hydrogen isotopes possible.

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Optically pure 2-C-methyl-d-erythritol 4-phosphate, a key intermediate in the mevalonate-independent route for isoprenoid biosynthesis, is conveniently synthesized from 1,2-O-isopropylidene-a-d-xylofuranose, including the possibility of radiolabeling of this substrate.