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Family-Based Tests of Association in the Presence of Linkage

✍ Scribed by Stephen L. Lake; Deborah Blacker; Nan M. Laird

Book ID
117853454
Publisher
American Society of Human Genetics
Year
2000
Tongue
English
Weight
236 KB
Volume
67
Category
Article
ISSN
0002-9297

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## Abstract Linkage and association analyses have played important roles in identifying susceptibility genes for complex diseases. Linkage tests and family‐based tests of association are often applied in the same data to help fine‐map disease loci or validate results. This paradigm increases effici