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The Effect of Family Structure on Linkage Tests Using Allelic Association

✍ Scribed by J.C. Whittaker; C.M. Lewis

Book ID
117852535
Publisher
American Society of Human Genetics
Year
1998
Tongue
English
Weight
191 KB
Volume
63
Category
Article
ISSN
0002-9297

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## Abstract The haplotype‐sharing correlation (HSC) method for association analysis using family data is revisited by introducing a permutation procedure for estimating region‐wise significance at each marker on a study segment. In simulation studies, the HSC method has a correct type 1 error rate