Reconstructing Parental Genotypes When Testing for Linkage in the Presence of Association
โ Scribed by Michael Knapp
- Book ID
- 115648663
- Publisher
- Elsevier Science
- Year
- 2001
- Tongue
- English
- Weight
- 112 KB
- Volume
- 60
- Category
- Article
- ISSN
- 0040-5809
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
## Abstract Genotyping errors can create a problem for the analysis of caseโparents data because some families will exhibit genotypes that are inconsistent with Mendelian inheritance. The problem with correcting Mendelian inconsistent genotype errors by regenotyping or removing families in which th
## Abstract We present a score for testing association in the presence of linkage for binary traits. The score is robust to varying degrees of linkage, and it is valid under any ascertainment scheme based on trait values as well as under population stratification. The score test is derived from a m
## Abstract Genotypeโbased likelihoodโratio tests (LRT) of association that examine maternal and parentโofโorigin effects have been previously developed in the framework of logโlinear and conditional logistic regression models. In the situation where parental genotypes are missing, the expectationโ