𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Expression of fetal antigens and tumor-specific antigens in SV40-transformed cells. I. Serological analysis of the antigenic specificities

✍ Scribed by Chou-Chik Ting; John R. Ortaldo; Ronald B. Herberman

Publisher
John Wiley and Sons
Year
1973
Tongue
French
Weight
534 KB
Volume
12
Category
Article
ISSN
0020-7136

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

The fetal antigens expressed in a variety of tumors have previously been shown to be different from tumor‐specific antigens. The present study on the expression of fetal antigens in various SV40‐transformed cells showed that more than one fetal antigen may be found in these cell lines, and that the expression of fetal antigens was not directly related to the function of the SV40 genome. These fetal antigens were not found in syngeneic spleen cells but were found in the normal spleens of some other strains of mice.

📜 SIMILAR VOLUMES

Expression of fetal antigens and tumor-s
Expression of fetal antigens and tumor-specific antigens in SV40-transformed cells. II. Tumor transplantation studies
✍ Chou-Chik Ting; Dennis Rodrigues; Ronald B. Herberman 📂 Article 📅 1973 🏛 John Wiley and Sons 🌐 French ⚖ 343 KB 👁 1 views

## Abstract The effect of immunization with fetal antigens and tumor‐specific antigens on the transplantation of SVT2, a BALB/c mouse tumor induced by Simian virus 40 (SV40), has been studied. Hyperimmunization with 5,000 R X‐irradiated, syngeneic fetuses of 1–2 weeks' gestation or syngeneic spleen

Expression of SV40 tumor antigen in SV40
Expression of SV40 tumor antigen in SV40 transformed teratocarcinoma-derived cell lines
✍ Helena R. Axelrod; Arnold J. Levine 📂 Article 📅 1980 🏛 John Wiley and Sons 🌐 English ⚖ 332 KB

## Abstract The relative importance of viral tumor antigen expression and the cellular background in the maintenance of a transformation phenotype was examined in five SV40‐transformed teratocarcinoma‐derived cell lines. These cell lines show qualitative differences in growth characteristics associ

Differences in the manifestation of viru
Differences in the manifestation of virus-specific surface antigen between cells transformed by sv40 and uv-irradiated sv40
✍ W. Klietmann; N. Seemayer 📂 Article 📅 1971 🏛 John Wiley and Sons 🌐 French ⚖ 729 KB

## Abstract Marked differences in the manifestation of SV40‐specific surface (S‐) antigen were found between hamster cell lines transformed __in vitro__ and __in vivo__ by SV40 and UV‐irradiated or photodynamically inactivated SV40. In the mixed hemagglutination reaction (MHA) cell lines induced by

Detection of specific surface antigens b
Detection of specific surface antigens by colony inhibition in cells transformed by papovavirus SV40
✍ Satvir S. Tevethia; Norman A. Crouch; Joseph L. Melnick; Fred Rapp 📂 Article 📅 1970 🏛 John Wiley and Sons 🌐 French ⚖ 661 KB

## Abstract Specific antigens at the surface of SV40‐transformed hamster cells were demonstrated by the in vitro colony inhibition and immunofluorescence tests. Antisera were prepared by inoculating hamsters either with purified SV40 or with human or marmoset SV40‐transformed cells. The inhibition

Properties of transformed hamster cells
Properties of transformed hamster cells containing sv40 tumor antigen in the cytoplasm
✍ Linda S. Richardson; Janet S. Butel 📂 Article 📅 1971 🏛 John Wiley and Sons 🌐 French ⚖ 791 KB

## Abstract The properties of hamster cells containing SV40 tumor (T) antigen in the cytoplasm, rather than the nucleus, were determined. Eight cell lines were established from eight tumors induced by hamster embryo fibroblasts transformed __in vitro__ by PARA (2cT)‐adenovirus 7. Six cell lines con

Detergent solubilization and partial pur
Detergent solubilization and partial purification of tumor specific surface and transplantation antigens from SV40-virus-transformed mouse cells
✍ Chungming Chang; Samuel J. Pancake; Samuel W. Luborsky; Peter T. Mora 📂 Article 📅 1977 🏛 John Wiley and Sons 🌐 French ⚖ 704 KB

## Abstract A solubilization technique employing 0.5% Triton X‐100 was developed to obtain both SV40 virus (SV40)‐induced tumor‐specific surface antigen(s) (TSSA) from SV40‐transformed mouse cells, as determined by a serum‐mediated microcytolytic assay, and tumor‐specific transplantation antigen(s)