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Esophageal cancer in Chinese population: no polymorphism in codon 149 of P21Waf1/Cip1 cyclin dependent kinase gene

โœ Scribed by Xi, Ya-Guang; Ding, Ke-Yue; Ren, Ying-Hui; Shen, Yan; Ke, Yang

Book ID
110067024
Publisher
Nature Publishing Group
Year
2002
Tongue
English
Weight
410 KB
Volume
21
Category
Article
ISSN
0950-9232

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WAF1/Cip1/Sdi1 (p21) is the prototype of a family of proteins that inhibit cyclin-dependent kinases and regulate cell cycle progression in eukaryotic cells. In addition to normal cell cycle progression, p21 is involved in growth suppression mediated by p53 and transforming growth factor beta (TGFbet