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Expression of the cyclin dependent kinase inhibitor p21WAF1/CIP1in oesophageal squamous cell carcinomas

✍ Scribed by K. Ohashi; Tetsuo Nemoto; Yoshinobu Eishi; Atsumi Matsuno; Kyoichi Nakamura; Katsuiku Hirokawa

Publisher: Springer
Year: 1997
Tongue: English
Weight: 479 KB
Volume: 430
Category: Article
ISSN: 1432-2307
DOI: 10.1007/s004280050048

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in signaling cellular growth arrest. In response to DNA damage, p21 is induced by the p53 gene, thereby playing a direct role in mediating p53-induced G 1 arrest.