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Enhanced antibody production of human-human hybridomas by retinoic acid

โœ Scribed by Yuichi Inoue; Mihoko Fujisawa; Masahiro Shoji; Shuichi Hashizume; Yoshinori Katakura; Sanetaka Shirahata


Book ID
110259373
Publisher
Springer
Year
2000
Tongue
English
Weight
111 KB
Volume
33
Category
Article
ISSN
0920-9069

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Improvement in the antibody productivity
โœ Keiji Iwamoto; Yasushi Shintani; Reiko Sasada; Tasuku Honjo; Kazuaki Kitano ๐Ÿ“‚ Article ๐Ÿ“… 1990 ๐Ÿ› Springer ๐ŸŒ English โš– 823 KB

The presence of a highly purified recombinant interleukin-2 (rIL-2) increased the production of immunoglobulin (IgM or IgG) by human-human hybridomas to 1.5-2.0 times the production by untreated cells. However, these cells did not react with anti-Tac (IL-2 receptor o0 antibody. To enhance the respon