MAb were derived from mice immunized with cells of the human neuroblastoma line IMR-32. Five hybridomas were selected according to their selective binding to human cell lines, tumors and normal tissues. One of them, CE7, reacted with all sympatho-adrenomedullary cells (neuroblastoma, ganglioneurobla
β¦ LIBER β¦
Production and Characterization of Human-Human and Human-Mouse Hybridomas Secreting Rh(D)-Specific Monoclonal Antibodies
β Scribed by G. MACDONALD; S. PRIMROSE; K. BIGGINS; J. M. BOWMAN; I. BERCZI; A. D. FRIESEN; A. H. SEHON
- Book ID
- 110860775
- Publisher
- John Wiley and Sons
- Year
- 1987
- Tongue
- English
- Weight
- 546 KB
- Volume
- 25
- Category
- Article
- ISSN
- 0300-9475
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## Abstract Hybridoma CE7 produces a murine antibody (yl/k) which binds to a 190βkDa cellβsurface glycoprotein of human neuroblasβtoma. Because of its tumor specificity, it has been used routinely in clinical pathology to confirm diagnosis of neuroblastoma. We have Isolated the gene segments coding
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