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Endogenous production of infectious Inoue-Melnick virus in a human meningioma cell line

✍ Scribed by Y. Nishibe; Dr. Y. K. Inoue; A. C. Hollinshead

Publisher: John Wiley and Sons
Year: 1987
Tongue: English
Weight: 357 KB
Volume: 23
Category: Article
ISSN: 0146-6615
DOI: 10.1002/jmv.1890230304

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✦ Synopsis

We investigated continuous production of Inoue-Melnick virus (IMV) in the MG-1 cell line, established from human meningioma. The infectious virus, identified as a type 1 virus, was mostly recovered extracellularly. Assay of MG-1 cells as infective centers indicated that most of the cells were capable of producing infectious virus. By immunofluorescence, more than 90% of the cells were found to have IMV-associated cytoplasmic antigen(s) (IMCA).

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