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Enantioselective one-pot synthesis of β-lactams from achiral 2-pyridylthioesters and aromatic imines

✍ Scribed by Rita Annunziata; Maurizio Benaglia; Mauro Cinquini; Franco Cozzi

Publisher: Elsevier Science
Year: 1995
Tongue: French
Weight: 191 KB
Volume: 36
Category: Article
ISSN: 0040-4039
DOI: 10.1016/0040-4039(94)02316-4

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## Abstract β‐Lactams VII are formed when ethoxyalkynes II are slowly added to boiling solutions of aromatic imines VI in xylene. In all probability aldoketenes III are intermediate products. The yields are moderate to good.