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Enantioselective Desymmetrization of meso Epoxides with Anilines Catalyzed by a Niobium Complex of a Chiral Multidentate Binol Derivative

✍ Scribed by Kenzo Arai; Matthew M. Salter; Yasuhiro Yamashita; Shū Kobayashi


Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
94 KB
Volume
46
Category
Article
ISSN
0044-8249

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## Abstract Catalyzed by the Mg complexes of BINOL derivatives, the enantioselective ring opening reaction of various __meso__‐epoxides proceeded smoothly with either aromatic or aliphatic amines as the nucleophiles to afford the corresponding chiral β‐amino alcohols in moderate‐to‐high yields with