Enantioselective deprotonation of two racemic cyclic carbonyl compounds by a chiral lithium amide
โ Scribed by M.B. Eleveld; H. Hogeveen
- Book ID
- 104218173
- Publisher
- Elsevier Science
- Year
- 1986
- Tongue
- French
- Weight
- 262 KB
- Volume
- 27
- Category
- Article
- ISSN
- 0040-4039
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๐ SIMILAR VOLUMES
Enantioselective deprotonation of 4-substituted cyclohexanones (1) in the presence of excess trimethylsilyl chloride was examined using chirai bidentate lithium amides ((R)-3~(R)-7) in THF. The solution structures of (R)-3a in THF in the presence and in the absence of lithium chloride were studied b
A highlyenantioaelectivedeprotonationof meso-epoxideswas achievedby a catalyticamount of a new chiral lithiumamide, derived from (ZS,3aS,7aS)-2-(pyrrolidin-l-ylmethyl)octahydrO indole, in the presenceof excesalithiumdiisopropylamideto afford the correspondingallylic alcoholderivatives up to9470ee. 0
## Stereochemistry of Enantioselective Deprotonation of 4-Substituted Cyclohexanones by Chiral Bidentate Lithium Amides. -Enantioselective deprotonation of 4-substituted cyclohexanones using chiral lithium amide bases such as (I) in the presence of excess trimethylsilyl chloride results in format