ChemInform Abstract: Chiral Bidentate Lithium Amides Having a Chiral Amide Nitrogen for Enantioselective Deprotonation of 4-tert-Butylcyclohexanone.
β Scribed by H. CHATANI; M. NAKAJIMA; H. KAWASAKI; K. KOGA
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 29 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0931-7597
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Enantioselective Deprotonation of 4-tert-Butylcyclohexanone by Fluorine-Containing Chiral Lithium Amides Derived from Ξ±-Phenethylamine. -The conversion of (I) to the corresponding chiral silyl enol ether using Ξ±-phenethylamine derived chiral lithium amides is investigated. The highest enantioselecti
## Stereochemistry of Enantioselective Deprotonation of 4-Substituted Cyclohexanones by Chiral Bidentate Lithium Amides. -Enantioselective deprotonation of 4-substituted cyclohexanones using chiral lithium amide bases such as (I) in the presence of excess trimethylsilyl chloride results in format
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