Electrochemical radiofluorination: Labeling of benzene with [18F]fluoride by nucleophilic substitution
โ Scribed by G. Reischl; G. J. Kienzle; H.-J. Machulla
- Book ID
- 110410106
- Publisher
- Springer
- Year
- 2002
- Tongue
- English
- Weight
- 96 KB
- Volume
- 254
- Category
- Article
- ISSN
- 1588-2780
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๐ SIMILAR VOLUMES
## Abstract Nucleophilic displacement of activated nitro groups by ^18^Fโfluoride ion is an efficient route to fluorineโ18 labeled aromatics, which can be obtained in the noโcarrierโadded state if required. The basic features of the fluorodenitration process are comparatively evaluated, and the in
## Abstract The efficient and rapid nucleophilic exchange of fluorine by fluorideโ^18^F ion in aromatic rings is reported here utilizing rubidiumโ^18^Fโfluoride in DMSO on model compounds. Specific activities in the 3 ร 10^4^ Ci/mol region are readily achievable. Nucleophilic substitution is shown