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Effects of tocopherols and 2,2′-carboxyethyl hydroxychromans on phorbol-ester-stimulated neutrophils

✍ Scribed by Zsuzsa Varga; Eszter Kosaras; Edina Komodi; Monika Katko; Istvan Karpati; Jozsef Balla; Gyorgy Paragh; Maria C. Aisa; Francesco Galli


Book ID
108187291
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
349 KB
Volume
19
Category
Article
ISSN
0955-2863

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The metabolites are 2,5,7,8-tetramethyl-2-(2-carboxyethyl)-6-hydroxychroman (␣-CEHC) and 2,7,8-trimethyl-2-(2carboxyethyl)-6-hydroxychroman (␥-CEHC, LLU-␣), respectively. ␣-CEHC is excreted mainly as glucuronide or sulfate conjugates in the urine. Here we describe a sensitive and reliable method to