Effect on male rats of the gastric instillation of methylcholanthrene in “heated” and “unheated” olive oil
✍ Scribed by Harry Shay; Charles Harris; Margot Gruenstein
- Publisher
- John Wiley and Sons
- Year
- 1951
- Tongue
- English
- Weight
- 516 KB
- Volume
- 4
- Category
- Article
- ISSN
- 0008-543X
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The eects of pretreatment with the enzyme inducers phenobarbital (PB) and 3methylcholanthrene (3-MC) and the enzyme inhibitor chloramphenicol (CM) on the pharmacokinetic and pharmacodynamic parameters of azosemide were examined after intravenous (IV) administration of azosemide, 10 mg kg 71 , to rat
Mammary turnours were induced in rats by intragastric administration of 3-methylcholanthrene. More than 75% of the tumours attained palpable size between 3 and I 1 weeks after the last dose of the carcinogen. Adrenalectomy did not inhibit the growth of tumours already present and appeared even to en