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The effect of adrenalectomy on the growth of mammary tumours induced by 3-methylcholanthrene in rats

✍ Scribed by P. M. Daniel; Marjorie M. L. Prichard

Publisher
John Wiley and Sons
Year
1967
Tongue
French
Weight
719 KB
Volume
2
Category
Article
ISSN
0020-7136

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✦ Synopsis

Mammary turnours were induced in rats by intragastric administration of 3-methylcholanthrene. More than 75% of the tumours attained palpable size between 3 and I 1 weeks after the last dose of the carcinogen. Adrenalectomy did not inhibit the growth of tumours already present and appeared even to encourage tumour growth. However, the stimulating effect of adrenalectomy was outweighed by the inhibition of tumour growth caused by subsequent removal of the ovaries.

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