Effect of tea root extract (TRE) on solid tumours induced by 3-methylcholanthrene in mice
✍ Scribed by T. Chaudhuri; P. Sur; A. Gomes; S. K. Das; M. Das; D. K. Ganguly
- Publisher
- John Wiley and Sons
- Year
- 1998
- Tongue
- English
- Weight
- 91 KB
- Volume
- 12
- Category
- Article
- ISSN
- 0951-418X
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✦ Synopsis
The antitumour effect of tea plant root extract (TRE) has been evaluated against a 3-methylcholanthrene (3-MC) induced solid tumour model in ICR mice. TRE inhibited the tumur weight and the tumours were found to be nonnecrotic. Superoxide dismutase (SOD), a free radical scavenger, in the sera of TRE treated tumour bearing mice was found to be significantly increased while the SOD level in untreated tumour bearing animals was low. Moreover, the enhanced level of thiobarbituric acid reactive substance (TBARS) in sera of tumour bearing mice were normalized upon TRE treatment.