The effects of pretreatment with the enzyme inducers, phenobarbital (PB) and 3-methylcholanthrene (3-MC), on the pharmacokinetic and pharmacodynamic parameters of bumetanide were examined in rats. The nonrenal clearance (19.3 vs 29.6 ml min-' per kg) of bumetanide increased significantly in PB treat
Effects of phenobarbital and 3-methylcholanthrene pretreatment on the pharmacokinetics and pharmacodynamics of furosemide in rats
โ Scribed by Young M. Choi; So H. Kim; Myung G. Lee
- Publisher
- John Wiley and Sons
- Year
- 1991
- Tongue
- English
- Weight
- 552 KB
- Volume
- 80
- Category
- Article
- ISSN
- 0022-3549
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