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Effect of Solution Conformation on Antibody Recognition of a Protein Core Epitope from Gastrointestinal Mucin (MUC2)

✍ Scribed by Katalin Uray; Judit Kajtár; Elemér Vass; Michael R. Price; Miklós Hollósi; Ferenc Hudecz


Book ID
115567383
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
116 KB
Volume
361
Category
Article
ISSN
0003-9861

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Human intestinal mucins are high molecular weight glycoproteins which protect and lubricate the epithelium of the gastrointestinal tract. In cases of malignant disease, mucins are abnormally expressed, overproduced or underglycosylated. This feature may enable the mucins to serve as tumour markers.