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Effect of naloxone on the locomotor stimulatory action of chlordiazepoxide in mice

โœ Scribed by Mario Sansone; Jerzy Vetulani

Book ID
113222851
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
270 KB
Volume
31
Category
Article
ISSN
0091-3057

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๐Ÿ“œ SIMILAR VOLUMES

Effects of repeated administration of ch
Effects of repeated administration of chlordiazepoxide on spontaneous locomotor activity in mice
โœ Mario Sansone ๐Ÿ“‚ Article ๐Ÿ“… 1979 ๐Ÿ› Springer ๐ŸŒ English โš– 191 KB

Spontaneous locomotor activity has been studied in mice treated with single or repeated doses (five daily injections) of chlordiazepoxide. The repeated administration enhanced the stimulatory action of the lower doses of the drug, while the depressant effect of the higher doses was reduced.

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Spontaneous locomotor activity was tested in CD-1 mice receiving subacutely (for 4 days) chlordiazepoxide (10 mg/kg) and then treated with d-amphetamine (0.5 or 1 mg/kg) and various doses of chlordiazepoxide (2.5, 5 or 10 mg/kg) separately or in combination. Chlordiazepoxide pretreatment enhanced th

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โœ Mario Sansone; Jozef Hano ๐Ÿ“‚ Article ๐Ÿ“… 1979 ๐Ÿ› Springer ๐ŸŒ English โš– 424 KB

Spontaneous locomotor activity has been studied in mice treated with chlordiazepoxide, atropine, and scopolamine, given alone or in combination. Chlordiazepoxide alone increased activity for a short time, while the two anticholinergic drugs produced longer lasting stimulatory effects. Locomotor stim