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Enhancement by chlordiazepoxide of the anticholinergic-induced locomotor stimulation in mice

โœ Scribed by Mario Sansone; Jozef Hano

Publisher
Springer
Year
1979
Tongue
English
Weight
424 KB
Volume
64
Category
Article
ISSN
0033-3158

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โœฆ Synopsis

Spontaneous locomotor activity has been studied in mice treated with chlordiazepoxide, atropine, and scopolamine, given alone or in combination. Chlordiazepoxide alone increased activity for a short time, while the two anticholinergic drugs produced longer lasting stimulatory effects. Locomotor stimulation was stronger when chlordiazepoxide and anticholinergics were given in combination.

๐Ÿ“œ SIMILAR VOLUMES

Scopolamine-induced locomotor stimulatio
Scopolamine-induced locomotor stimulation in mice: Effect of diazepam and a benzodiazepine antagonist
โœ Mario Sansone ๐Ÿ“‚ Article ๐Ÿ“… 1982 ๐Ÿ› Springer ๐ŸŒ English โš– 195 KB

The benzodiazepine diazepam and the benzodiazepine antagonist Ro 15-1788 were tested alone or in combination for their influence on scopolamine-induced locomotor stimulation in mice. The benzodiazepine antagonist had no effect by itself, but prevented the enhancement of scopolamine-induced locomotor