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Naloxone potentiates the depressant effect of chlordiazepoxide on spontaneous activity in mice

โœ Scribed by Rodgers, R.J.; Randall, Jill; Kelway, Barbara


Book ID
122528076
Publisher
Elsevier Science
Year
1985
Tongue
English
Weight
206 KB
Volume
58
Category
Article
ISSN
0304-3940

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Effects of repeated administration of ch
โœ Mario Sansone ๐Ÿ“‚ Article ๐Ÿ“… 1979 ๐Ÿ› Springer ๐ŸŒ English โš– 191 KB

Spontaneous locomotor activity has been studied in mice treated with single or repeated doses (five daily injections) of chlordiazepoxide. The repeated administration enhanced the stimulatory action of the lower doses of the drug, while the depressant effect of the higher doses was reduced.