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Effect of inhibitors of eicosanoid metabolism in murine collagen-induced arthritis

✍ Scribed by Don E. Griswold; Leonard M. Hillegass; Paul C. Meunier; Michael J. Dimartino; Nabil Hanna

Publisher
John Wiley and Sons
Year
1988
Tongue
English
Weight
683 KB
Volume
31
Category
Article
ISSN
0004-3591

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✍ Florence Apparailly; DaniΓ¨le NoΓ«l; Virginie Millet; Andrew H. Baker; Gina Lisign πŸ“‚ Article πŸ“… 2001 πŸ› John Wiley and Sons 🌐 English βš– 630 KB

Objective. The imbalance between matrix metalloproteinases (MMPs) 1, 3, and 9 and their specific inhibitor, tissue inhibitor of metalloproteinases 1 (TIMP-1), is a critical step in cartilage injury and angiogenesis in arthritis. To explore the therapeutic potential of TIMP-1 gene transfer in erosive