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Biphasic effect of interferon-γ in murine collagen-induced arthritis

✍ Scribed by Marie-Christophe Boissier; Gilles Chiocchia; Natacha Bessis; Julia Hajnal; Gianni Garotta; Ferdinando Nicoletti; Catherine Fournier

Publisher
John Wiley and Sons
Year
1995
Tongue
English
Weight
984 KB
Volume
25
Category
Article
ISSN
0014-2980

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Interferon-γ regulates susceptibility to collagen-induced arthritis through suppression of interleukin-17
✍ Cong-Qiu Chu; David Swart; Dina Alcorn; Joel Tocker; Keith B. Elkon 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 317 KB

## Abstract ## Objective The enhanced expression of experimental arthritis in the absence of interferon‐γ (IFNγ) suggests that IFNγ suppresses arthritis. Interleukin‐17 (IL‐17) is a pivotal T cell cytokine in arthritis, and in vitro studies have indicated that IFNγ suppresses IL‐17 production. We